An NMR based phosphodiesterase assay Academic Article uri icon

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abstract

  • A phosphodiesterase (PDE) assay based on 1D 1H NMR to monitor the hydrolysis of cyclic nucleotides directly, without requiring tags or the addition of exogenous reagents.

authors

  • Akimoto, Madoka
  • Yu, Tianning
  • Moleschi, Kody
  • Van, Katherine
  • Anand, Ganesh S
  • Melacini, Giuseppe

publication date

  • July 25, 2020