Journal article
Bioprosthetic heart valves of the future
Abstract
Glutaraldehyde-fixed bioprosthetic heart valves (GBHVs), derived from pigs or cows, undergo structural valve deterioration (SVD) over time, with calcification and eventual failure. It is generally accepted that SVD is due to chemical processes between glutaraldehyde and free calcium ions in the blood. Valve companies have made significant progress in decreasing SVD from calcification through various valve chemical treatments. However, there are …
Authors
Manji RA; Ekser B; Menkis AH; Cooper DKC
Journal
Xenotransplantation, Vol. 21, No. 1, pp. 1–10
Publisher
Wiley
Publication Date
1 2014
DOI
10.1111/xen.12080
ISSN
0908-665X