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A randomized trial evaluating virus-specific...
Journal article

A randomized trial evaluating virus-specific effects of a combination probiotic in children with acute gastroenteritis

Abstract

Gastroenteritis accounts for nearly 500,000 deaths in children younger than 5 years annually. Although probiotics have been touted as having the potential to expedite diarrhea resolution, recent clinical trials question their effectiveness. A potential explanation is a shift in pathogens following the introduction of a rotavirus vaccine. Here, we report the results of a multi-center, double-blind trial of 816 children with acute gastroenteritis …

Authors

Freedman SB; Xie J; Nettel-Aguirre A; Pang X-L; Chui L; Williamson-Urquhart S; Schnadower D; Schuh S; Sherman PM; Lee BE

Journal

Nature Communications, Vol. 11, No. 1,

Publisher

Springer Nature

DOI

10.1038/s41467-020-16308-3

ISSN

2041-1723