Journal article
QF‐PCR rapid aneuploidy screen and aCGH analysis of cell free fetal (cff) DNA in supernatant of compromised amniotic fluids (AF)
Abstract
OBJECTIVE: The aim of this study was to determine whether cell free fetal (cff) DNA in residual amniotic fluid (AF) supernatant obtained from bloody, low-volume and late gestation samples can be used for prenatal diagnosis by quantitative fluorescence polymerase chain reaction (QF-PCR) and array comparative genomic hybridization (aCGH).
METHOD: A total of 49 compromised AFs were analyzed in this case-control, double-blinded study. The samples …
Authors
Madjunkova S; Li CT; Vlasschaert M; Adams M; Chitayat D; Maire G; Kolomietz E
Journal
Prenatal Diagnosis, Vol. 34, No. 10, pp. 970–976
Publisher
Wiley
Publication Date
October 2014
DOI
10.1002/pd.4405
ISSN
0197-3851