Journal article
Higher vs Lower Positive End-Expiratory Pressure in Patients With Acute Lung Injury and Acute Respiratory Distress Syndrome: Systematic Review and Meta-analysis
Abstract
CONTEXT: Trials comparing higher vs lower levels of positive end-expiratory pressure (PEEP) in adults with acute lung injury or acute respiratory distress syndrome (ARDS) have been underpowered to detect small but potentially important effects on mortality or to explore subgroup differences.
OBJECTIVES: To evaluate the association of higher vs lower PEEP with patient-important outcomes in adults with acute lung injury or ARDS who are receiving …
Authors
Briel M; Meade M; Mercat A; Brower RG; Talmor D; Walter SD; Slutsky AS; Pullenayegum E; Zhou Q; Cook D
Journal
JAMA: The Journal of the American Medical Association, Vol. 303, No. 9, pp. 865–873
Publisher
American Medical Association (AMA)
Publication Date
March 3, 2010
DOI
10.1001/jama.2010.218
ISSN
0098-7484