Journal article
Low-Molecular-Weight Heparin in the Treatment of Patients with Venous Thromboembolism
Abstract
BACKGROUND: Low-molecular-weight heparin is known to be safe and effective for the initial treatment of patients with proximal deep-vein thrombosis. However, its application to pulmonary embolism or previous episodes of thromboembolism has not been studied.
METHODS: We randomly assigned 1021 patients with symptomatic venous thromboembolism to fixed-dose, subcutaneous low-molecular-weight heparin (reviparin sodium) or adjusted-dose, intravenous …
Authors
Büller HR; Gent M; Gallus AS; Ginsberg J; Prins MH; Baildon R
Journal
The New England Journal of Medicine, Vol. 337, No. 10, pp. 657–662
Publisher
Massachusetts Medical Society
Publication Date
September 4, 1997
DOI
10.1056/nejm199709043371001
ISSN
0028-4793