A Mechanistic Study of the Hydrolysis of Poly[N,N‑(dimethylamino)ethyl acrylates] as Charge-Shifting Polycations

Polycations are used extensively in applications ranging from enhanced oil recovery to biomaterials. Poly­[N,N-(dimethylamino)­ethyl acrylate] (PDMAEA) has attracted interest for biomaterial applications because of its rapid hydrolysis; however, the mechanism of hydrolysis and the conditions that affect degradation often appear amiss in the field. In this report, a detailed 1H NMR spectroscopy study of the hydrolysis of PDMAEA was carried out …