Medical Management of Primary Hyperparathyroidism

Medical management could be an option in selected patients with primary hyperparathyroidism with failed surgery, contraindication to surgery, or unwilling to undergo surgery. Calcium intake should not be restricted and vitamin deficiency/insufficiency should be corrected in all patients. Bisphosphonates and estrogen therapy increase bone mineral density (BMD) and decrease bone turnover, but have no significant impact on serum calcium or PTH …