Treatment of Hypoparathyroidism with Calcium and Vitamin D

Calcium and vitamin D metabolite therapy is currently the cornerstone of therapy in hypoparathyroidism. Limitations to therapy include the development of hypercalciuria and hyperphosphatemia with an increased risk of extra-skeletal calcification, as well as impairment in renal function. Wide fluctuations in serum calcium, with this therapeutic approach, also significantly impact quality of life. Advances in therapy include the availability of …