Journal article
Targeting bacterial secretion systems: benefits of disarmament in the microcosm.
Abstract
Secretion systems are used by many bacterial pathogens for the delivery of virulence factors to the extracellular space or directly into host cells. They are attractive targets for the development of novel anti-virulence drugs as their inactivation would lead to pathogen attenuation or avirulence, followed by clearance of the bacteria by the immune system. This review will present the state of knowledge on the assembly and function of type II, …
Authors
Baron C; Coombes B
Journal
Infectious Disorders - Drug Targets, Vol. 7, No. 1, pp. 19–27
Publisher
Bentham Science Publishers
Publication Date
March 2007
DOI
10.2174/187152607780090685
ISSN
1871-5265