The relative efficacy of nine osteoporosis medications for reducing the rate of fractures in post-menopausal women

BackgroundIn the absence of head-to-head trials, indirect comparisons of randomized placebo-controlled trials may provide a viable option to assess relative efficacy. The purpose was to estimate the relative efficacy of reduction of fractures in post-menopausal women, and to assess robustness of the results.MethodsA systematic literature review of multiple databases identified randomized placebo-controlled trials with nine drugs for …