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Is it possible to define resistance to...
Journal article

Is it possible to define resistance to acetylsalicylic acid and P2Y12 blockers at the patient's bedside?

Abstract

Multiple assays exist to measure antiplatelet effects of acetylsalicylic acid and clopidogrel, and numerous studies have demonstrated an association between incomplete inhibition with these drugs and risk of cardiovascular events. Simple point-of-care assays are potentially suitable for bedside use, and cutoffs for antiplatelet drug "resistance" diagnosis have been proposed. However, many assays remain poorly standardized and validated, …

Authors

Eikelboom JW; Hankey GJ

Journal

Dialogues in Cardiovascular Medicine, Vol. 16, No. 1, pp. 21–48

Publication Date

September 5, 2011

ISSN

1272-9949