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Use of sodium–glucose cotransporter-2 inhibitors...
Journal article

Use of sodium–glucose cotransporter-2 inhibitors and risk of acute kidney injury in older adults with diabetes: a population-based cohort study

Abstract

BACKGROUND: Regulatory agencies warn about the risk of acute kidney injury (AKI) after the initiation of sodium-glucose cotransporter-2 (SGLT2) inhibitors. Our objective was to quantify the 90-day risk of AKI in older adults after initiation of SGLT2 inhibitors in routine clinical practice. METHODS: We conducted a population-based retrospective cohort study in Ontario, Canada, involving adults with diabetes who were aged 66 years or older and …

Authors

Iskander C; Cherney DZ; Clemens KK; Dixon SN; Harel Z; Jeyakumar N; McArthur E; Muanda FT; Parikh CR; Paterson JM

Journal

Canadian Medical Association Journal, Vol. 192, No. 14, pp. e351–e360

Publisher

Joule

Publication Date

April 6, 2020

DOI

10.1503/cmaj.191283

ISSN

0820-3946