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Journal article

Human pilot studies reveal the potential of a vitronectin: growth factor complex as a treatment for chronic wounds

Abstract

Several different advanced treatments have been used to improve healing in chronic wounds, but none have shown sustained success. The application of topical growth factors (GFs) has displayed some potential, but the varying results, high doses and high costs have limited their widespread adoption. Many treatments have ignored the evidence that wound healing is driven by interactions between extracellular matrix proteins and GFs, not just GFs …

Authors

Upton Z; Wallace HJ; Shooter GK; van Lonkhuyzen DR; Yeoh‐Ellerton S; Rayment EA; Fleming JM; Broszczak D; Queen D; Sibbald RG

Journal

International Wound Journal, Vol. 8, No. 5, pp. 522–532

Publisher

Wiley

Publication Date

October 2011

DOI

10.1111/j.1742-481x.2011.00859.x

ISSN

1742-4801