Journal article
SAS is amplified predominantly in surface osteosarcoma
Abstract
The development of several types of human tumors is related to amplification of genes that are involved in cell growth. The protein products of these genes give the cells a selective growth advantage. The q13-15 region of chromosome 12 is frequently altered in human sarcomas, and the SAS gene has been identified in an amplification unit mapping to this region. Gene amplification of SAS was analyzed to determine the frequency of genetic …
Authors
Noble‐Topham SE; Kandel RA; Burrow SR; Bell RS; Eppert K; Meltzer PS; Andrulis IL
Journal
Journal of Orthopaedic Research®, Vol. 14, No. 5, pp. 700–705
Publisher
Wiley
Publication Date
September 1996
DOI
10.1002/jor.1100140504
ISSN
0736-0266