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Calcitonin gene‐related peptide regulation of...
Journal article

Calcitonin gene‐related peptide regulation of glial cell‐line derived neurotrophic factor in differentiated rat myotubes

Abstract

Glial cell-line derived neurotrophic factor (GDNF) is the most potent trophic factor for motoneuron survival and neuromuscular junction formation. GDNF is upregulated in injured or denervated skeletal muscle and returns to normal levels following reinnervation. However, the mechanism by which GDNF is regulated in denervated muscle is not well understood. The nerve-derived neurotransmitter calcitonin gene-related peptide (CGRP) is upregulated …

Authors

Rosa E; Cha J; Bain JR; Fahnestock M

Journal

Journal of Neuroscience Research, Vol. 93, No. 3, pp. 514–520

Publisher

Wiley

Publication Date

March 2015

DOI

10.1002/jnr.23512

ISSN

0360-4012