Serotonin reuptake and receptor blockers

Blockade of postsynaptic serotonin receptors, which differentiates these agents from other drug classes. Nefazodone and trazodone also inhibit serotonin reuptake in the presynaptic neuron and are subclassified as 'serotonin antagonist and reuptake inhibitors.' Nefazodone has demonstrated efficacy in randomize d controlled trials of major depressive disorder, however, this agent was taken off the market in some countries due to concerns about …