Journal article
The Clinical Significance of Tenascin-C Splice Variant Expression in Chondrosarcoma
Abstract
OBJECTIVES: Tenascin-C (TNC) is an oligomeric glycoprotein of the extracellular matrix that is prominently expressed in malignant tumors. The purpose of this study was: (1) to determine the in vitro TNC splicing pattern in cultured human chondrocytes and chondrosarcoma cells, (2) to determine the in vivo TNC splicing pattern in clinical chondrosarcoma specimens, and (3) to perform survival analysis based on the TNC splicing pattern of the tumor …
Authors
Ghert MA; Jung ST; Qi W-N; Harrelson JM; Erickson HP; Block JA; Scully SP
Journal
Oncology, Vol. 61, No. 4, pp. 306–314
Publisher
Karger Publishers
Publication Date
2001
DOI
10.1159/000055338
ISSN
0030-2414