Journal article
Effect of Whole Body Hyperthermia and BCNU on the Development of Radiation Myelitis in the Rat
Abstract
A radiant heat device was used to study the interaction of 41.8 degrees C whole body hyperthermia (WBH), radiation (40 Gy) and the lipophilic anti-neoplastic agent BCNU in the development of myelitis in the rat spinal cord. The addition of WBH and BCNU neither precipitated myelitis acutely nor shortened the latency before the onset of neurological signs in irradiated animals.
Authors
Neville AJ; Robins HI; Martin P; Gilchrist KW; Dennis WH; Steeves RA
Journal
International Journal of Radiation Biology, Vol. 46, No. 4, pp. 417–420
Publisher
Taylor & Francis
Publication Date
January 1984
DOI
10.1080/09553008414551601
ISSN
0955-3002