Journal article
Differential Regulation of Adiponectin Receptor Gene Expression by Adiponectin and Leptin in Myotubes Derived from Obese and Diabetic Individuals
Abstract
OBJECTIVE: This study aimed to investigate the regulation of adiponectin receptors 1 (AdipoR1) and 2 (AdipoR2) gene expression in primary skeletal muscle myotubes, derived from human donors, after exposure to globular adiponectin (gAd) and leptin.
RESEARCH METHODS AND PROCEDURES: Four distinct primary cell culture groups were established [Lean, Obese, Diabetic, Weight Loss (Wt Loss); n = 7 in each] from rectus abdominus muscle biopsies obtained …
Authors
McAinch AJ; Steinberg GR; Mollica J; O'Brien PE; Dixon JB; Macaulay SL; Kemp BE; Cameron‐Smith D
Journal
Obesity, Vol. 14, No. 11, pp. 1898–1904
Publisher
Wiley
Publication Date
November 2006
DOI
10.1038/oby.2006.221
ISSN
1930-7381