New Anticoagulants Hirudin and Hirulog in the Treatment of Acute Coronary Syndromes

Thrombio plays a central role in thrombogenesis, It activates platelets, converts fibrinogen to tibrin, and activates factor XIII, which cross-links the fibrin thereby rendering it more resistant to lysis. Thrombin also arnplifies its own genertion by activating factors VII and V key coractors in the activation of factor X and prothrombin, respectively. Given the importance of thrombin in acute coronary syndromes the goal of most current …