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Actions of cardiotoxin on cytosolic free Ca2+ in...
Journal article

Actions of cardiotoxin on cytosolic free Ca2+ in the presence of a calcium-free environment, calcium channel blockers and the polyamine spermine in vascular smooth muscle and endothelial cells

Abstract

The effects of calcium-free, calcium channel blockers and polyamines on cardiotoxin (CTX) induced contraction of rat thoracic aorta and bovine pulmonary artery endothelial cells was investigated using both contractility and calcium imaging studies, respectively. Exposure of aortic rings to 15 μM CTX in calcium-free and high calcium (7 mM) conditions respectively, yielded minimal contraction. The selective and non-selective calcium channel …

Authors

Cheung S; Kwan TK; Huang SJ; Kwan CY

Journal

Biomedical Research India, Vol. 11, No. 2, pp. 131–136

Publication Date

December 1, 2000

ISSN

0970-938X