Relationships between event-related potentials and intracranial responses to auditory target detection: Brief report

Simultaneous scalp ERPs and intracranial frontal and intracranial temporal ERP-like responses were obtained from nine temporal lobe epilepsy patients. Deep frontal, but not temporal, waveforms were consistent across sites, hemispheres, and subjects. Consistent latency and polarity relationships were also seen between scalp and frontal intracranial waveforms. A component of the same polarity and latency as the surface N1 appeared in all deep frontal records. Given the lack of amplitude gradients across 4 cm, this suggests a common generator for this frontal depth component and scalp-recorded Nl located in more posterior regions. Frontal intracranial waveforms displayed components of opposite polarity but similar latency to scalp-recorded features P2, N2, and P3. Therefore, generators for the frontal intracranial Nl-like component and the remaining frontal components may reside at different locations. The generators for these remaining components may reside between the anterior cingulum and the scalp. © 1992 Raven Press, Ltd., New York.