Fractional synthetic rate of skeletal muscle protein during testosterone infusion

Testosterone (T) administration is known to increase muscle anabolism. However, traditional injections may not be maximally effective in the burned patient due to increased lipogenesis and lipid storage. Therefore, the effects of T infusion on skeletal muscle protein synthesis were investigated in normal male volunteers. Three subjects received 30 mg of methyl-testosterone infusion or the carrier (Intralipid) over a five hour period. Subjects …