Journal article
Premature expression of a muscle fibrosis axis in chronic HIV infection
Abstract
BackgroundDespite the success of highly active antiretroviral therapy (HAART), HIV infected individuals remain at increased risk for frailty and declines in physical function that are more often observed in older uninfected individuals. This may reflect premature or accelerated muscle aging.MethodsSkeletal muscle gene expression profiles were evaluated in three uninfected independent microarray datasets including young (19 to 29 years old), …
Authors
Kusko RL; Banerjee C; Long KK; Darcy A; Otis J; Sebastiani P; Melov S; Tarnopolsky M; Bhasin S; Montano M
Journal
Skeletal Muscle, Vol. 2, No. 1,
Publisher
Springer Nature
Publication Date
December 2012
DOI
10.1186/2044-5040-2-10
ISSN
2044-5040