Journal article
Prior Pacemaker Implantation and Clinical Outcomes in Patients With Heart Failure and Preserved Ejection Fraction
Abstract
OBJECTIVES: This study examined the relationship between prior pacemaker implantation and clinical outcomes in patients with heart failure with preserved ejection fraction (HFpEF).
BACKGROUND: Conventional right ventricular pacing causes electrical and mechanical left ventricular dyssynchrony and may worsen left ventricular systolic dysfunction and HF. Whether conventional pacing is also associated with worse outcomes in HFpEF is unknown.
Authors
Shen L; Jhund PS; Docherty KF; Petrie MC; Anand IS; Carson PE; Desai AS; Granger CB; Komajda M; McKelvie RS
Journal
JACC Heart Failure, Vol. 7, No. 5, pp. 418–427
Publisher
Elsevier
Publication Date
May 2019
DOI
10.1016/j.jchf.2018.12.006
ISSN
2213-1779
Fields of Research (FoR)
Sustainable Development Goals (SDG)
Medical Subject Headings (MeSH)
AgedAged, 80 and overAngiotensin II Type 1 Receptor BlockersBenzimidazolesBiphenyl CompoundsCardiac Pacing, ArtificialCardiovascular DiseasesCause of DeathDeath, Sudden, CardiacFemaleHeart FailureHospitalizationHumansIrbesartanMaleMiddle AgedMineralocorticoid Receptor AntagonistsMortalityPacemaker, ArtificialPrognosisProportional Hazards ModelsRandomized Controlled Trials as TopicSpironolactoneStroke VolumeTetrazolesVentricular Dysfunction, Left