Bayesian approach to the assessment of the population-specific risk of inhibitors in hemophilia A patients: a case study

BACKGROUND: Developing inhibitors is a rare event during the treatment of hemophilia A. The multifacets and uncertainty surrounding the development of inhibitors further complicate the process of estimating inhibitor rate from the limited data. Bayesian statistical modeling provides a useful tool in generating, enhancing, and exploring the evidence through incorporating all the available information. METHODS: We built our Bayesian analysis …