Chapter
Genetic Approaches in Human Embryonic Stem Cells and their Derivatives: Prospects for Regenerative Medicine
Abstract
This chapter reviews current protocols to maintain human embryonic stem cells (hESCs), genetic approaches to modifying undifferentiated hESCs, differentiation of hESCs into multiple lineages and transplantation of their derivatives, and genetic manipulation of hESC-derived progenies and also discusses the potential applications of genetic modifications of hESCs and their derivatives in the context of regenerative medicine. Knock-in/knockout …
Authors
Ji J; Zhong B; Bhatia M
Book title
Principles of Regenerative Medicine
Pagination
pp. 179-198
Publication Date
December 1, 2011
DOI
10.1016/B978-0-12-381422-7.10009-4