The implications of oxidative stress in tardive dyskinesia

Typical antipsychotic drugs are widely used in the treatment of schizophrenia and other psychotic disorders. Unfortunately their use is often associated with the development of behavioural supersensitivity as well as acute and delayed extra-pyramidal side effects (EPS) including Parkinson's like symptoms, tardive dyskinesia (TD) and akathisia. Recently, some of the second generation antipsychotic drugs such as risperidone have also been shown …