Journal article
Downregulation of microRNAs 145-3p and 145-5p Is a Long-term Predictor of Postmenopausal Breast Cancer Risk: The ORDET Prospective Study
Abstract
BACKGROUND: miRNAs have been implicated in the regulation of key metabolic, inflammatory, and malignant pathways; hence, they might be considered both predictors and players of cancer development.
METHODS: Using a case-control study design nested in the ORDET prospective cohort study, we addressed the possibility that specific mRNAs can serve as early predictors of breast cancer incidence in postmenopausal women. We compared leukocyte miRNA …
Authors
Muti P; Sacconi A; Hossain A; Donzelli S; Ben Moshe NB; Ganci F; Sieri S; Krogh V; Berrino F; Biagioni F
Journal
Cancer Epidemiology Biomarkers & Prevention, Vol. 23, No. 11, pp. 2471–2481
Publisher
American Association for Cancer Research (AACR)
Publication Date
November 1, 2014
DOI
10.1158/1055-9965.epi-14-0398
ISSN
1055-9965