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Investigating Bcl-2 family protein-protein...
Conference

Investigating Bcl-2 family protein-protein interactions using a high-speed multiplexing confocal FLIM microscope

Abstract

Quantitative measurement of protein-protein interaction is important for many biological processes, including cell growth, intercellular communication, gene expression and apoptosis. Förster Resonance Energy Transfer (FRET) provides a molecular level ruler to measure the distance, within a few nanometers, between two proteins. FRET can be measured by changes in fluorescence lifetime of the fluorophors by Fluorescence lifetime imaging microscopy …

Authors

Hirmiz N; Tsikouras A; Osterlund EJ; Richards M; Kun J; Andrews DW; Fang Q

Volume

11076

Publisher

SPIE, the international society for optics and photonics

Publication Date

July 31, 2019

DOI

10.1117/12.2526906

Name of conference

Advances in Microscopic Imaging II

Conference proceedings

Progress in biomedical optics and imaging

ISSN

1605-7422