Three-dimensional Model of Gastric Pacemaking Using Finite-elements and Stochastically Coupled Oscillators

In this paper we develop preliminary simplified mathematical models of the tissue level that can produce slow wave propagation phenomenon in a realistically shaped deformable structure with both electro-mechanical and mechano-electric feedbacks which would enable us to study effects of ICC-SMC coupling. First we develop the computational models which can account for heterogeneous phase shifts between ICC cells in the pacemaking network. These …