Some critical problems associated with the tissue engineering of vital organs: Strategies for vascularisation and immune acceptance

The LIFE Initiative was created with the goal of using tissue engineering to create an essentially unlimited supply of vital organs (heart, kidney, liver) for transplantation. Among the many critical technologies that need to be developed to enable this, one is the ability to create an internal vasculature and thereby provide oxygen to all cells. One such strategy is to use angiogenic growth factors in our case using microencapsulated …