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Salvage therapy for progressive,...
Journal article

Salvage therapy for progressive, treatment-refractory or recurrent pediatric medulloblastoma: a systematic review protocol

Abstract

BackgroundCentral nervous system tumors remain the leading cause of cancer-related mortality amongst children with solid tumors, with medulloblastoma (MB) representing the most common pediatric brain malignancy. Despite best current therapies, patients with recurrent MB experience have an alarmingly high mortality rate and often have limited therapeutic options beyond inadequate chemotherapy or experimental clinical trials. Therefore, a …

Authors

Adile AA; Kameda-Smith MM; Bakhshinyan D; Banfield L; Salim SK; Farrokhyar F; Fleming AJ

Journal

Systematic Reviews, Vol. 9, No. 1,

Publisher

Springer Nature

Publication Date

December 2020

DOI

10.1186/s13643-020-01307-8

ISSN

2046-4053