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Efficacy and safety of gastrointestinal bleeding...
Journal article

Efficacy and safety of gastrointestinal bleeding prophylaxis in critically ill patients: systematic review and network meta-analysis

Abstract

OBJECTIVE: To determine, in critically ill patients, the relative impact of proton pump inhibitors (PPIs), histamine-2 receptor antagonists (H2RAs), sucralfate, or no gastrointestinal bleeding prophylaxis (or stress ulcer prophylaxis) on outcomes important to patients. DESIGN: Systematic review and network meta-analysis.

Authors

Wang Y; Ye Z; Ge L; Siemieniuk RAC; Wang X; Wang Y; Hou L; Ma Z; Agoritsas T; Vandvik PO

Journal

The BMJ, Vol. 368, ,

Publisher

BMJ

DOI

10.1136/bmj.l6744

ISSN

0959-8138