A recent series of papers have devised and successfully used a methodology for the detection and characterization of domains in laterally heterogeneous vesicles
viasmall-angle neutron scattering. This methodology is in seeming contradiction to similar work devised by Knoll, Haas, Stuhrmann, Füldner, Vogel & Sackmann [ J. Appl. Cryst.(1981), 14, 191–202]. The present paper shows how these results may be reconciled.