Ingenol mebutate: an introduction Journal Articles

abstract

• The incidence of nonmelanoma skin cancer continues to increase. While surgical excision remains the mainstay of treatment, growing demand from patients for effective, tissue-sparing approaches with good cosmetic results has led to the development of novel therapeutic agents. Several studies have reported on the safety and efficacy of topical ingenol mebutate gel, a derivative of the plant Euphorbia peplus, in the treatment of actinic keratosis and superficial basal cell carcinoma. An understanding of the history, mechanism of action, and recent trial evidence for this emerging therapy can assist physicians in counseling patients on available treatment options and in selecting appropriate therapy.

authors

• Fallen, Robyn
• Gooderham, Melinda

status

• published 

publication date

• February 2012

has subject area

• Administration, Cutaneous (MeSH)
• Antineoplastic Agents, Phytogenic (MeSH)
• Carcinoma, Basal Cell (MeSH)
• Diterpenes (MeSH)
• Euphorbia (MeSH)
• Humans (MeSH)
• Keratosis, Actinic (MeSH)
• Skin Neoplasms (MeSH)

published in

• Skin therapy letter  Journal

keywords

• Administration, Cutaneous
• Antineoplastic Agents, Phytogenic
• Carcinoma, Basal Cell
• Diterpenes
• Euphorbia
• Humans
• Keratosis, Actinic
• Skin Neoplasms

PubMed ID

• 22358305

start page

• 1

end page

• 3

volume

• 17

issue

• 2