Journal article
Amaranth suppresses the mutagenicity of 2-acetylaminofluorene by lowering the concentration of nadph in top agar
Abstract
Addition of 1 mg amaranth (FD&C Red No. 2) to the top agar of Salmonella/S9 assay plates decreased the yield of revertants induced by 20 micrograms 2-acetylaminofluorene (AAF) by over 50% and additional amaranth completely eliminated the mutagenic response. Similar suppression of AAF mutagenicity was seen with sulfonazo III, another azo dye. The suppressive effect of amaranth was greatest at low S9 concentrations and decreased as the amount of …
Authors
McCalla DR; Kaiser C; Lu C; Messier F; Quilliam MA
Journal
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, Vol. 82, No. 2, pp. 201–211
Publisher
Elsevier
Publication Date
7 1981
DOI
10.1016/0027-5107(81)90150-0
ISSN
0027-5107