Journal article
Cytotoxicity and DNA damage to mammalian cells by nitrofurans
Abstract
Nitrofurazone, nitrofurantoin, furazolidone, furaltadone and N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide (FANFT) were toxic to cultured mouse L cells. The extent of toxocity and the rate of reduction of nitrofurazone increased markedly as the oxygen content of the incubation medium was lowered. The toxic effect of nitrofurans was decreased by addition of serum and was much greater in phosphate-buffered saline containing glucose (PSG) than in …
Authors
Olive PL; McCalla DR
Journal
Chemico-Biological Interactions, Vol. 16, No. 2, pp. 223–233
Publisher
Elsevier
Publication Date
February 1977
DOI
10.1016/0009-2797(77)90131-4
ISSN
0009-2797