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Antiretroviral Drug Concentrations in Breastmilk,...
Journal article

Antiretroviral Drug Concentrations in Breastmilk, Maternal HIV Viral Load, and HIV Transmission to the Infant

Abstract

BACKGROUND: Concentration of antiretroviral (ARV) drug found in plasma, and amounts of drug excreted into breastmilk, may affect HIV viral load and potentially perinatal HIV transmission. METHODS: In this cohort study with 2-phase sampling, we included mothers randomized to postpartum maternal ARVs or daily infant nevirapine during 28 weeks of breastfeeding in the Breastfeeding, Antiretrovirals, and Nutrition study. Among these, we included all …

Authors

Davis NL; Corbett A; Kaullen J; Nelson JAE; Chasela CS; Sichali D; Hudgens MG; Miller WC; Jamieson DJ; Kourtis AP

Journal

JAIDS Journal of Acquired Immune Deficiency Syndromes, Vol. 80, No. 4, pp. 467–473

Publisher

Wolters Kluwer

Publication Date

April 1, 2019

DOI

10.1097/qai.0000000000001941

ISSN

1525-4135