Journal article
Anti-inflammatory effects of simvastatin in subjects with hypercholesterolemia
Abstract
AIMS: Beneficial effects of statins in preventing cardiovascular events may depend, at least in part, on their anti-inflammatory action. The aim of the study was to assess the influence of simvastatin and aspirin on serum levels of C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) in hypercholesterolemic subjects.
METHODS AND RESULTS: In 33 asymptomatic men with total cholesterol (TC) >6.5 mmol l(-1) and …
Authors
Musial J; Undas A; Gajewski P; Jankowski M; Sydor W; Szczeklik A
Journal
International Journal of Cardiology, Vol. 77, No. 2-3, pp. 247–253
Publisher
Elsevier
Publication Date
February 2001
DOI
10.1016/s0167-5273(00)00439-3
ISSN
0167-5273