Journal article
APOE and cortical superficial siderosis in CAA: Meta-analysis and potential mechanisms.
Abstract
OBJECTIVE: To assess potential mechanisms of cortical superficial siderosis (cSS), a central MRI biomarker in cerebral amyloid angiopathy (CAA), we performed a collaborative meta-analysis of APOE associations with cSS presence and severity.
METHODS: We pooled data from published studies reporting APOE genotype and MRI assessment of cSS in 3 distinct settings: (1) stroke clinic patients with symptomatic CAA (i.e., lobar intracerebral hemorrhage, …
Authors
Charidimou A; Zonneveld HI; Shams S; Kantarci K; Shoamanesh A; Hilal S; Yates PA; Boulouis G; Na HK; Pasi M
Journal
Neurology, Vol. 93, No. 4, pp. e358–e371
Publisher
Wolters Kluwer
Publication Date
July 23, 2019
DOI
10.1212/wnl.0000000000007818
ISSN
0028-3878