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Attenuated inflammatory response of...
Journal article

Attenuated inflammatory response of monocyte-derived macrophage from patients with BD: a preliminary report

Abstract

BackgroundInnate immune system dysfunction has been recognized as an important element in the pathophysiology of bipolar disorder (BD). We aimed to investigate whether there are differences in the response of macrophages derived from patients in the early stages and late stages of BD and healthy subjects.MethodsHuman monocytes purified from peripheral blood mononuclear cells (PBMCs) of patients with BD type I (n = 18)—further classified into …

Authors

Ascoli BM; Parisi MM; Bristot G; Antqueviezc B; Géa LP; Colombo R; Kapczinski F; Guma FTCR; Brietzke E; Barbé-Tuana FM

Journal

International Journal of Bipolar Disorders, Vol. 7, No. 1,

Publisher

Springer Nature

Publication Date

December 2019

DOI

10.1186/s40345-019-0148-x

ISSN

2194-7511