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Translating genomic analyses into improved...
Journal article

Translating genomic analyses into improved management of coronary artery disease

Abstract

Human genetic variation can modulate pathophysiologic processes that alter susceptibility to complex disease. Recent genomic analyses have sought to identify how common genetic variation alters susceptibility to coronary artery disease (CAD). From genome-wide association studies (GWAS), common genetic variants in several novel chromosomal loci have been associated with CAD. GWAS identified the 9p21 locus as the strongest independent genetic CAD …

Authors

Johansen CT; Lanktree MB; Hegele RA

Journal

Future Cardiology, Vol. 6, No. 4, pp. 507–521

Publisher

Taylor & Francis

Publication Date

July 2010

DOI

10.2217/fca.10.28

ISSN

1479-6678