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Single versus multifraction radiotherapy for...
Journal article

Single versus multifraction radiotherapy for spinal cord compression: A systematic review and meta-analysis

Abstract

BACKGROUND: While multifraction radiotherapy (RT) regimens (MFRT) have been considered the standard of care in patients with metastatic epidural spinal cord compression (MESCC) with limited prognosis, recent randomized evidence has demonstrated that single fraction RT (SFRT) may be equivalent in terms of functional and overall outcomes. A systematic review and meta-analysis was conducted to determine the effects of SFRT compared to short course …

Authors

Donovan EK; Sienna J; Mitera G; Kumar-Tyagi N; Parpia S; Swaminath A

Journal

Radiotherapy and Oncology, Vol. 134, , pp. 55–66

Publisher

Elsevier

Publication Date

May 2019

DOI

10.1016/j.radonc.2019.01.019

ISSN

0167-8140