The (mis) use of bone resorption markers in the context of bisphosphonate exposure, dental surgery and osteonecrosis of the jaw

OBJECTIVES: To evaluate the argument for use of bone resorption markers in patients exposed to bisphosphonates and requiring dental surgery to prevent development of osteonecrosis of the jaw. METHODS: Review of literature. RESULTS: 5 primary reports and a number of reviews were considered. CONCLUSIONS: There is insufficient evidence to recommend use of bone resorption markers in patients exposed to bisphosphonates prior to dental surgery as a routine test to assess risk of osteonecrosis of the jaw.