Current approaches to the treatment of advanced-stage non-Hodgkin's lymphoma.

Non-Hodgkin's lymphomas (NHLs) are a diverse group of malignant diseases whose clinical behaviour and treatment are distinct from those of Hodgkin's disease. In advanced-stage NHL certain histologic subtypes grow relatively slowly, initially produce few symptoms and, even when untreated, are associated with survival that is usually measured in years. Other, less favourable subtypes grow more rapidly, produce symptoms earlier and result in rapid …