Conference
Creating a Population Model for PK-Tailored Dosing Using Real-World Data from the Web-Accessible Population Pharmacokinetic Service-Hemophilia (WAPPS-Hemo) Platform
Abstract
Abstract
Objective: The Web-Accessible Population Pharmacokinetic Service-Hemophilia (WAPPS-Hemo) platform allows hemophilia treaters to estimate individual PK parameters for clotting factor concentrates using only a few blood samples drawn from their patients. Population pharmacokinetic (PopPK) models used with WAPPS-Hemo are usually built using clinical trial data provided by drug manufacturers. These trials can be …
Authors
Chelle P; Yeung C; Boix SB; Morales JC; Ozelo MC; Vericat JEM; Iorio A; Spears J; Mir R; Edginton AN
Volume
132
Publisher
American Society of Hematology
Publication Date
November 29, 2018
DOI
10.1182/blood-2018-99-115308
Conference proceedings
Blood
Issue
Supplement 1
ISSN
0006-4971