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Safe Start of Ibrutinib in Patients with Chronic...
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Safe Start of Ibrutinib in Patients with Chronic Lymphocytic Leukemia and Uncontrolled Autoimmune Hemolytic Anemia

Abstract

Abstract It is estimated that 4-10% of patients with chronic lymphocytic leukemia (CLL) will develop autoimmune hemolytic anemia (AIHA) over the course of their disease. Ibrutinib has proven to be effective in treatment of relapsed, refractory, 17p deleted, and treatment naïve CLL. The effect of ibrutinib on AIHA in the context of CLL has not been established since patients with active hemolysis were excluded from major …

Authors

Garcia-Horton A; St. Bernard R; Lazo-Langner A; Xenocostas A; Mangel J; Howson-Jan K; Lam S; Hsia CC

Volume

132

Publisher

American Society of Hematology

Publication Date

November 29, 2018

DOI

10.1182/blood-2018-99-120129

Conference proceedings

Blood

Issue

Supplement 1

ISSN

0006-4971