Cardiovascular safety and glycemic control of glucagon-like peptide-1 receptor agonists for type 2 diabetes mellitus: A pairwise and network meta-analysis

Abstract

AIMS: Integrating evidence from all randomized controlled trials (RCTs) of glucagon-like peptide-1 receptor agonists (GLP-1s) to assess the safety of cardiovascular disease (CVD) and efficacy of glycemic control. METHODS: Besides performing pairwise meta-analysis, network meta-analysis of all RCTs was used to combine direct and indirect estimates of the effect of GLP-1 with placebo, active comparator drugs (ACD), or another GLP-1 agent with …

Authors

Sun F; Yu K; Wu S; Zhang Y; Yang Z; Shi L; Ji L; Zhan S

Journal

Diabetes Research and Clinical Practice, Vol. 98, No. 3, pp. 386–395

Publisher

Elsevier

Publication Date

December 2012

DOI

10.1016/j.diabres.2012.09.004

ISSN

0168-8227

Associated Experts

Yuan Zhang

Assistant Professor (Part-Time), Faculty of Health Sciences

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